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When the level of blood calcium drops below 8.5 milligrams p

When the level of blood calcium drops below 8.5 milligrams per deciliter (mg/dL) [1 dL = 100 millili… Show more When the level of blood calcium drops below 8.5 milligrams per deciliter (mg/dL) [1 dL = 100 milliliters (mL)], the parathyroid gland that monitors blood calcium is stimulated to release parathyroid hormone (PTH) into the blood. PTH binds to receptor proteins on cells of several tissues: (1) PTH stimulates the kidneys to reabsorb calcium, increasing the blood calcium concentration and decreasing the amount excreted in the urine; (2) PTH stimulates osteoclast cells in the bone to release more calcium from bone, thus increasing blood calcium concentration; (3) if the hormone calcitriol is present (calcitriol is derived from vitamin D), PTH increases the rate of calcium uptake across the intestine wall into the blood, thus increasing blood calcium concentration. (Hint: sensors and integrators can sometimes be the same). In the space provided below, create a flow chart to illustrate the homeostatic control system. Identify the variable and set point, and include the following components: stimulus, sensor, integrator, effector, response and negative feedback. To help you get started, complete the template below. Do the same for Part II on the next page. • Show less

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